Cameron, I had similar thoughts when I was brainstorming how one could record their everything on the web, but always stepped back when I was handling high throughput data. I think the idea of LaBlog is a good start, but blog is not something tailor-built for science / scientific research, will this model sustainable? I am starting a blog to elaborate more on the topic.

David's concern is also worth-noting. Generally, scientist would prefer a stable and controllable system for recording their data. Recording things on the web should not be more costly and time-consuming than doing on a paper.