We're still at a manageable situation with the CombiUgi project, with about 30 results in our table
http://spreadsheets.google.com/pub?key=plwwufp30hfpUERhse9y5Kw

There are many more experiments than that but they were flawed or failed in some way so didn't make it to the master table. But all the attempts are available here:
http://usefulchem.wikispaces.com/All+Reactions

In terms of database storage, we are lucky in that ChemSpider is willing to help us store all the final spectra (including hopefully the X-ray crystal structures shortly). As for monitoring data, organic chemistry does not burden the researcher with unmanageable amounts (at least how we have been doing it)

Cameron, as you and I have discussed, we are probably going to end up in a similar place - we are just taking different routes. We're starting with making our experiments as human-understandable as possible and not much concern for format. But we'll be (hopefully soon) inching towards translating these protocols into versions that are much more machine readable (and probably less human readable).

If you saw the last proposal I discussed on my blog, this is the kind of thing we'd like to work on with ChemSpider (and anyone else interested in collaborating of course).