A couple of weeks ago there was a significant fracas over Daniel MacArthur‘s tweeting from a Cold Spring Harbour Laboratory meeting.  This was followed in pretty quick succession by an article in Nature discussing the problems that could be caused when the details of presentations no longer stop at the walls of the conference room and all of these led to a discussion (see also friendfeed discussions) about how to make it clear whether you are happy or not with your presentation being photographed, videoed, or live blogged. A couple …

I, and many others have spent the last week thinking about Wave and I have to say that I am getting more, rather than less, excited about the possibilities that this represents. All of the below will have to remain speculation for the moment but I wanted to walk through two use cases and identify how the concept of a collaborative automated document will have an impact. In this post I will start with the drafting and publication of a paper because it is an easier step to think about. …

I spent two days this week visiting Peter Murray-Rust and others at the Unilever Centre for Molecular Informatics at Cambridge. There was a lot of useful discussion and I learned an awful lot that requires more thinking and will no doubt result in further posts. In this one I want to relay a conversation we had over lunch with Peter, Jim Downing, Nico Adams, Nick Day and Rufus Pollock that seemed extremely productive. It should be noted that what follows is my recollection so may not be entirely accurate and …

There are a set of memes that seem to be popping up with increasing regularity in the last few weeks. The first is that more of the outputs of scientific research need to be published. Sometimes this means the publication of negative results, other times it might mean that a community doesn’t feel they have an outlet for their particular research field. The traditional response to this is “we need a journal” for this. Over the years there have been many attempts to create a “Journal of Negative Results”. There …

I hold no particular candle for traditional peer review. I think it is inefficient, poorly selective, self reinforcing, often poorly done, and above all, far too slow. However I also agree that it is the least worst system we have available to us.  Thus far, no other approaches have worked terribly well, at least in the communication of science research. And as the incumbent for the past fifty years or so in the post of ‘generic filter’ it is owed some respect for seniority alone.
So I am considering writing a …

This post is an opinion piece and not a rigorous objective analysis. It is fair to say that I am on the record as and advocate of the principles behind PLoS ONE and am also in favour of post publication peer review and this should be read in that light. [ed I've also modified this slightly from the original version because I got myself mixed up in an Excel spreadsheet]
To me, anonymous peer review is, and always has been, broken. The central principle of the scientific method is that …

A story of two major retractions from a well known research group has been getting a lot of play over the last few days with a News Feature (1) and Editorial (2) in the 15 May edition of Nature. The story turns on claim that Homme Hellinga’s group was able to convert the E. coli ribose binding protein into a Triose phosphate isomerase (TIM) using a computational design strategy. Two papers on the work appeared, one in Science (3) and one in J Mol Biol (4). However another group, having …

As has been noted in a few places, Neil Withers, one of the editors of soon to be newest Nature journal, Nature Chemistry put out a request last week for input on a range of issues to do with how people use journals, formats, and technical widgets. Egon Willighagen, Rich Apodaca, and Oscar the Journal Munching Robot (masquerading as Peter Murray-Rust, or is that the other way around?) have already posted responses. Here I want to add my own thoughts and possibly amplify some of the points others have made.
As …